Endogenous proteases and phosphatases in cell and tissue extracts may degrade proteins or remove modifications, affecting downstream detection. Appropriate inhibitors help prevent these changes during sample preparation.

• An optimized cocktail of protease and phosphatase inhibitors protects proteins during extraction and purification. Components include pepstatin, aprotinin and leupeptin. Suitable for protein purification, Western blotting, Co-IP, immunofluorescence and immunohistochemistry.